Package: GRAB
Type: Package
Title: Genome-Wide Robust Analysis for Biobank Data (GRAB)
Version: 0.2.3
Date: 2025-08-25
Authors@R: c(person(given = "Wenjian",
                    family = "Bi",
                    role = "aut"),
             person(given = "Wei",
                    family = "Zhou",
                    role = "aut"),
             person(given = "Rounak",
                    family = "Dey",
                    role = "aut"),
             person(given = "Zhangchen",
                    family = "Zhao",
                    role = "aut"),
             person(given = "Seunggeun",
                    family = "Lee",
                    role = "aut"),
             person(given = "Woody",
                    family = "Miao",
                    role = "cre",
                    email = "miaolin@pku.edu.cn"))
Description: Provides a comprehensive suite of genome-wide association study (GWAS) methods
    specifically designed for biobank-scale data. The package offers computationally efficient
    and robust association tests for time-to-event traits (e.g., Bi et al., 2020 
    <doi:10.1016/j.ajhg.2020.06.003>), ordinal categorical traits (e.g., Bi et al., 2021 
    <doi:10.1016/j.ajhg.2021.03.019>), and longitudinal traits (Xu et al., 2025 
    <doi:10.1038/s41467-025-56669-1>). Additionally, it includes functions for 
    simulating genotype and phenotype data to support research and method development.
License: GPL (>= 2)
Encoding: UTF-8
Depends: R (>= 3.5.0)
Imports: dplyr, data.table, mvtnorm, Matrix, RSQLite, lme4, ordinal,
        survival, Rcpp, RcppParallel, igraph
Suggests: dbplyr, optparse, tidyr, R.utils, SKAT
LinkingTo: Rcpp, RcppArmadillo, RcppParallel, BH
RoxygenNote: 7.3.2
NeedsCompilation: yes
Packaged: 2025-08-19 07:04:11 UTC; Woody
Author: Wenjian Bi [aut],
  Wei Zhou [aut],
  Rounak Dey [aut],
  Zhangchen Zhao [aut],
  Seunggeun Lee [aut],
  Woody Miao [cre]
Maintainer: Woody Miao <miaolin@pku.edu.cn>
Repository: CRAN
Date/Publication: 2025-08-20 02:30:02 UTC
Built: R 4.4.1; aarch64-apple-darwin20; 2025-08-25 22:32:45 UTC; unix
Archs: GRAB.so.dSYM
