# Exact Sequential Analysis for Poisson and Binomial Data

## Documentation for package ‘Sequential’ version 4.5

- DESCRIPTION file.

## Help Pages

Sequential-package | Analysis Support, Critical Values, Power, Time to Signal and Sample Size for Sequential Analysis with Poisson and Binomial Data.
Analyze.Binomial | Function for group sequential analyses for binomial data, without the need to know group sizes a priori.
Analyze.CondPoisson | Function to conduct group sequential analyses for conditional Poisson data without the need to know group sizes a priori.
Analyze.Multinomial | Function for group sequential analyses for multinomial data, without the need to know group sizes a priori.
Analyze.Poisson | Function to conduct group sequential analyses for Poisson data without the need to know group sizes a priori.
Analyze.wBinomial | Function for group sequential analyses of multiple weighted binomial endpoints, without the need to know group sizes a priori.
AnalyzeRegression.Binomial | Function for MaxSPRT regression analyses with binary/binomial data, without the need to know group sizes a priori.
AnalyzeRegression.CondPoisson | Function for MaxSPRT regression analyses with conditional Poisson data, without the need to know group sizes a priori.
AnalyzeRegression.Poisson | Function for MaxSPRT regression analyses with Poisson data, without the need to know group sizes a priori.
AnalyzeSetUp.Binomial | Function to set up input parameters before using the 'Analyze.Binomial' function for the first time.
AnalyzeSetUp.CondPoisson | Function to set up input parameters before using the 'Analyze.CondPoisson' function for the first time.
AnalyzeSetUp.Multinomial | Function to set up input parameters before using the 'Analyze.Multinomial' function for the first time.
AnalyzeSetUp.Poisson | Function to set up input parameters before using the 'Analyze.Poisson' function for the first time.
AnalyzeSetUp.wBinomial | Function to set up input parameters before using the 'Analyze.wBinomial' function for the first time.
AnalyzeSetUpRegression.Binomial | Function to set up input parameters before using the 'AnalyzeRegression.Binomial' function for the first time.
AnalyzeSetUpRegression.CondPoisson | Function to set up input parameters before using the 'AnalyzeRegression.CondPoisson' function for the first time.
AnalyzeSetUpRegression.Poisson | Function to set up input parameters before using the 'AnalyzeRegression.Poisson' function for the first time.
ConfidenceInterval.Binomial | Confidence Interval for the Relative Risk Following a Sequential Test with Binary Data.
CV.Binomial | Calculates exact critical values for group and continuous sequential analysis with binomial data.
CV.CondPoisson | Critical values for continuous sequential CMaxSPRT for Poisson data with limited information from historical cohort.
CV.Poisson | Critical values for group and continuous sequential analysis with Poisson data.
Optimal.Binomial | Optimal alpha spending for minimizing expected time to signal for continuous and group sequential analysis with binomial data.
Performance.AlphaSpend.Binomial | Calculates performance and signaling threshold for user-defined alpha spending for sequential analysis with binomial data.
Performance.AlphaSpend.CondPoisson | Calculates performance and signaling thresholds for user-defined alpha spending for sequential analysis with conditional Poisson data.
Performance.AlphaSpend.Poisson | Calculates performance and signaling thresholds for user-defined alpha spending for sequential analysis with Poisson data.
Performance.Binomial | Statistical power, expected time to signal and expected sample size for group and continuous sequential analysis with binomial data.
Performance.CondPoisson | Statistical power, expected time to signal and expected sample size for the continuous sequential CMaxSPRT for Poisson data with limited information from historical cohort.
Performance.Poisson | Calculates statistical power, expected time to signal and expected sample size for group and continuous sequential analysis with Poisson data.
Performance.Threshold.Binomial | Statistical Performance and Alpha Spending For User-defined Signaling Threshold With Binomial Data.
Performance.Threshold.CondPoisson | Performance and alpha spending for user-defined signaling threshold for sequential analysis with conditional Poisson data.
Performance.Threshold.Poisson | Performance and alpha spending for user-defined signaling threshold for sequential analysis with Poisson data.
SampleSize.Binomial | Sample size calculation for continuous sequential analysis with binomial data.
SampleSize.CondPoisson | Sample size calculation for the continuous sequential CMaxSPRT for Poisson data with limited information from historical cohort.
SampleSize.Poisson | Sample size calculation for continuous sequential analysis with Poisson data.
Sequential | Analysis Support, Critical Values, Power, Time to Signal and Sample Size for Sequential Analysis with Poisson and Binomial Data.