Using Historical Controls for Designing Phase II Clinical Trials

Documentation for package ‘hctrial’ version 0.1.0

hctrial-package	hctrial: A package for designing phase 2 clinical trials adjusting for heterogeneous populations.
hctrial	hctrial: A package for designing phase 2 clinical trials adjusting for heterogeneous populations.
hist_end	Adjust a design based on historical controls at the end of the study using the covariate data of the patients accrued in stage 2.
hist_interim	Adjust a design based on historical controls at interim using the covariate data of the patients accrued in stage 1.
hist_start	Initializes a design based on historical controls before the start of the study.
strat_end	Adjust a subspace stratified design at the end of the study.
strat_interim	Adjust a subspace stratified design at interim.
strat_start	Initializes a subspace stratified design before the start of the study.