How to apply EUCAST rules

Matthijs S. Berends

15 October 2019


What are EUCAST rules? The European Committee on Antimicrobial Susceptibility Testing (EUCAST) states on their website:

EUCAST expert rules are a tabulated collection of expert knowledge on intrinsic resistances, exceptional resistance phenotypes and interpretive rules that may be applied to antimicrobial susceptibility testing in order to reduce errors and make appropriate recommendations for reporting particular resistances.

In Europe, a lot of medical microbiological laboratories already apply these rules (Brown et al., 2015). Our package features their latest insights on intrinsic resistance and exceptional phenotypes (version 9.0, 2019). Moreover, the eucast_rules() function we use for this purpose can also apply additional rules, like forcing ampicillin = R in isolates when amoxicillin/clavulanic acid = R.

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Benefit for empiric therapy success estimation

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