YPInterimTesting: Interim Monitoring Using Adaptively Weighted Log-Rank Test in Clinical Trials

Provide monitoring boundaries for interim testing using the adaptively weighted log-rank test developed by Yang and Prentice (2010 <doi:10.1111/j.1541-0420.2009.01243.x>). The package use a re-sampling method to obtain stopping boundaries in sequential designs. The output consists of stopping boundaries at the interim looks along with nominal p-values defined as the probability of the test exceeding the specific observed value or critical value, regardless of the test behavior at other looks. The asymptotic distribution of the test statistics of the adaptively weighted log-rank test at the interim looks is examined in Yang (2017, pre-print).

Version: 0.1.0
Imports: Rcpp
LinkingTo: Rcpp
Published: 2017-11-17
Author: Daewoo Pak and Song Yang
Maintainer: Daewoo Pak <heavyrain.pak at gmail.com>
License: GPL (≥ 3)
NeedsCompilation: yes
Materials: README NEWS
CRAN checks: YPInterimTesting results

Downloads:

Reference manual: YPInterimTesting.pdf
Package source: YPInterimTesting_0.1.0.tar.gz
Windows binaries: r-devel: YPInterimTesting_0.1.0.zip, r-release: YPInterimTesting_0.1.0.zip, r-oldrel: YPInterimTesting_0.1.0.zip
OS X El Capitan binaries: r-release: YPInterimTesting_0.1.0.tgz
OS X Mavericks binaries: r-oldrel: YPInterimTesting_0.1.0.tgz

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