bmass: Bayesian Multivariate Analysis of Summary Statistics

Multivariate tool for analyzing genome-wide association study results in the form of univariate summary statistics. The goal of 'bmass' is to comprehensively test all possible multivariate models given the phenotypes and datasets provided. Multivariate models are determined by assigning each phenotype to being either Unassociated (U), Directly associated (D) or Indirectly associated (I) with the genetic variant of interest. Test results for each model are presented in the form of Bayes factors, thereby allowing direct comparisons between models. The underlying framework implemented here is based on the modeling developed in "A Unified Framework for Association Analysis with Multiple Related Phenotypes", M. Stephens (2013) <doi:10.1371/journal.pone.0065245>.

Version: 1.0.3
Depends: R (≥ 3.3.0)
Imports: utils, stats
Suggests: testthat, knitr, rmarkdown
Published: 2019-05-17
Author: Michael Turchin [aut, cre], Matthew Stephens [aut], Peter Carbonetto [ctb]
Maintainer: Michael Turchin <mturchin20 at uchicago.edu>
BugReports: https://github.com/mturchin20/bmass/issues
License: GPL (≥ 3)
URL: https://github.com/mturchin20/bmass
NeedsCompilation: no
Citation: bmass citation info
Materials: NEWS
CRAN checks: bmass results

Documentation:

Reference manual: bmass.pdf
Vignettes: bmass Introduction – Simulated Data
bmass Introduction – Real Data

Downloads:

Package source: bmass_1.0.3.tar.gz
Windows binaries: r-devel: bmass_1.0.3.zip, r-release: bmass_1.0.3.zip, r-oldrel: bmass_1.0.3.zip
macOS binaries: r-release (arm64): bmass_1.0.3.tgz, r-oldrel (arm64): bmass_1.0.3.tgz, r-release (x86_64): bmass_1.0.3.tgz

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