Changes from Version 1.4 to 1.5 * overhauled graphical user interface and report. Changes from Version 1.3 to 1.4 * changed the reduced alphabet of amino acids, * improved prediction model, * enhanced output of signalHsmm print and summary functions, * enhanced graphical user interface. Changes from Version 1.2.1 to 1.3 * improved read_uniprot to check features other than signal peptide and look for specific phrases in protein description. Changes from Version 1.2 to 1.2.1 * fixed systematic error in a cleavage site prediction.